Laboratory Scientist II - Genome Analyst

• Classification: Lab Scientist II
• Union: HSAA FAC PROF/TECH
• Unit and Program: Genetics & Genomics South
• Primary Location: Alberta Children's Hospital
• Location Details: Eligible to work remotely within Alberta
• Multi-Site: Not Applicable
• FTE: 1.00
• Posting End Date: 18-MAY-2023
• Employee Class: Regular Full Time
• Date Available: 19-JUN-2023
• Hours per Shift: 7.75
• Length of Shift in weeks: 2
• Shifts per cycle: 10
• Shift Pattern: Days
• Days Off: Saturday/Sunday
• Minimum Salary: $42.53
• Maximum Salary: $56.50
• Vehicle Requirement: Not Applicable

Completion of a Master of Medical Laboratory Science degree or a related scientific discipline.

MSc or PhD in molecular genetics, molecular genomics, genetic counselling, molecular biology, biotechnology, biochemistry, or related discipline is required. Minimum 3 years of experience, annotating, and classifying genetic and genomic variants (SNVs, indels, CNVs), using HGVS nomenclature. Classes/education in human genetics and/or mechanisms of disease. Proficient in the use of public genetic databases, including but not limited to GnomAD, ClinVar, OMIM, DGV. Proficient in performing literature searches. Proficient in the use of genomic analysis software (eg. JSI, Alamut, Bluegnome, NxClinical). Proficient in the use of database/spreadsheet applications. Understanding of next generation sequencing methods including library preparation, sequencing, mapping, variant calling, annotation and quality metrics is required. Proven critical thinking, analytical, problem solving, planning, and decision-making skills. Strong attention to detail as well as superior organizational and time management skills with ability to prioritize work and deliver accurate work under stressful conditions. Ability to work, collaborate and interact with laboratory, operations and medical scientific staff in a manner consistent with APL/AHS values. Demonstrated ability to deal with conflicting and changing priorities, deadlines, and duties. English fluency with exceptional verbal and written communication skills.

Formal training in variant interpretation, certificate or graduation from an accredited program would be an asset. Experience in a clinical genetics or molecular biology laboratory. Experience annotating and classifying human genetic and genomic variants in a clinical setting. Knowledge of the theory and practice of human cytogenetic analysis including proper use of ISCN nomenclature is an asset. CMLTA registration is an asset but not a requirement.